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Villumsen, M., B. I. von Osmanski, K. E. Lomborg, and K. S. Benthien. 2025. “Evidence for the Use of Patient-Reported Outcome Measures in the Treatment of Patients With Noncommunicable Diseases: Systematic Review.” JMIR Med Inform 13:e66160. <\/span>Doi: 10.2196\/66160. Medinform.jmir.org\/2025\/1\/e66160\/<\/a><\/p>\n Download Resume som pdf<\/a><\/p>\n Af Marie Villumsen, Klinisk epidemiolog, Cand.scient.publ., Ph.d., <\/span>marie.villumsen@regionh.dk <\/a>Kirstine Skov Benthien, Seniorforsker, klinisk sygeplejespecialist og lektor, Cand.scient.san., Ph.d., <\/span>kirstine.skov.benthien.01@regionh.dk<\/a><\/em><\/p>\n Resum\u00e9 Metode Resultater Konklusion Implikationer for praksis <\/p>\n <\/p>\n","protected":false},"excerpt":{"rendered":" Villumsen, M., B. I. von Osmanski, K. E. Lomborg, and K. S. 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\n<\/span><\/strong>Introduktion
\n<\/span><\/strong>Patientrapporterede oplysninger (PRO) anvendes i stigende grad til screening og beslutningsst\u00f8tte i sundhedsv\u00e6senet, selvom evidensgrundlaget hidtil har v\u00e6ret uklart. Form\u00e5let med denne systematiske litteraturgennemgang var at vurdere evidensen for brugen af PRO i klinisk praksis blandt patienter med diabetes, KOL, hjertesygdom, leddegigt (RA) og inflammatorisk tarmsygdom (IBD).<\/span><\/p>\n
\n<\/span><\/strong>Vi udf\u00f8rte en systematisk gennemgang af publicerede randomiserede kontrollerede fors\u00f8g, hvor PRO blev anvendt i klinisk sammenh\u00e6ng, enten alene eller som del af en beslutningsalgoritme. Studierne inkluderede voksne patienter med de n\u00e6vnte sygdomme. Litteraturs\u00f8gningen blev udf\u00f8rt i PubMed\/ MEDLINE, CINAHL, EMBASE og Web of Science frem til februar 2023. To forskere screenede uafh\u00e6ngigt titler, abstracts og fuldtekster. Tre forskere vurderede risiko for bias med Cochrane RoB 2-v\u00e6rkt\u00f8jet. Resultaterne blev pr\u00e6senteret i en narrativ syntese og i opsummeret form.<\/span><\/p>\n
\n<\/span><\/strong>S\u00f8gningen gav 21.203 artikler, 686 fuldtekstartikler blev screenet, og 56 originalstudier blev inkluderet i gennemgangen. Studierne omfattede patienter med hjertesygdomme (30,4%), KOL (23,2%), diabetes (17,9%), IBD (16,1%) og leddegigt (10,7%) samt patienter med blandede diagnoser (1,8%). Mens alle indsatser havde et element af screening, varierede de \u00f8vrige form\u00e5l mellem beslutningsst\u00f8tte (33,9%), dialogst\u00f8tte (16,1%) og erstatning af fysiske bes\u00f8g (8,9%). Den mest udbredte PRO-administrationsform var telefonen, efterfulgt af hjemmesider, h\u00e5ndholdte apparater kun anvendt til PRO og apps. Endepunkterne omfattede bl.a. sygdomsaktivitet, brug af sundhedsv\u00e6senet, d\u00f8delighed, mental vel-v\u00e6re, livskvalitet, og egenomsorg. Seks studier med lav risiko for bias viste en positiv effekt eller non-inferioritet af PRO-indsatsen.<\/span><\/p>\n
\n<\/span><\/strong>Evidensen for klinisk anvendelse af PRO er begr\u00e6nset. Kun f\u00e5 studier har lav risiko for bias, og samlet set viser evidensen ingen entydig forbedring i patienternes helbred, livskvalitet, kontakt til sundhedsv\u00e6senet, overlevelse eller omkostninger. Der er desuden observeret risiko for u\u00f8nskede effekter.<\/span><\/p>\n
\n<\/span><\/strong>Resultaterne peger p\u00e5 et behov for yderligere udvikling og forskning frem for direkte implementering af PRO i behandlingen af patienter med kroniske sygdomme.<\/span><\/p>\n