{"id":20249,"date":"2025-09-27T12:39:37","date_gmt":"2025-09-27T10:39:37","guid":{"rendered":"https:\/\/sygeplejevidenskab.dk\/?p=20249"},"modified":"2025-09-27T12:40:28","modified_gmt":"2025-09-27T10:40:28","slug":"en-sugetablet-med-maelkesyrebakterier-og-l-arginin-som-nyt-vaaben-mod-huller-i-taenderne","status":"publish","type":"post","link":"https:\/\/sygeplejevidenskab.dk\/index.php\/2025\/09\/27\/en-sugetablet-med-maelkesyrebakterier-og-l-arginin-som-nyt-vaaben-mod-huller-i-taenderne\/","title":{"rendered":"En sugetablet med m\u00e6lkesyrebakterier og L-arginin som nyt v\u00e5ben mod huller i t\u00e6nderne?"},"content":{"rendered":"

\"\"<\/p>\n

P\u00f8rksen CJ, Keller MK, Damholt A, Frederiksen AKS, Ekstrand KR, Markvart M, Larsen T, Bakhshandeh A. The effect of a lozenge combining prebiotic arginine and probiotics on caries increment in children during 10-12 months, a randomized clinical trial. J Dent. 2023 Aug;135:104599.<\/span> 10.1016\/j.jdent.2023.104599. Epub 2023 Jun 24. Erratum in: J Dent. 2024 Feb;141:104807. D<\/span>oi: 10.1016\/j.jdent.2023.104807. PMID: 37356561<\/a>.<\/span><\/p>\n

Download Resume som pdf<\/a><\/p>\n

Af Camilla Juhl P\u00f8rksen. Tandl\u00e6ge, tandplejer og ph.d.Co-founder og ejer, CariGuard<\/a>. Ansat ved 3Shape. <\/span>camilla@cariguard.dental<\/span><\/em><\/p>\n

Resum\u00e9
\n<\/span>Introduktion
\n<\/span><\/strong>Huller i t\u00e6nderne (caries) er den mest udbredte ikke-smitsomme sygdom globalt og rammer if\u00f8lge WHO ca. 2,5 milliarder mennesker. Forebyggelse med fluoridtandpasta er veldokumenteret, men ikke altid tilstr\u00e6kkelig. Som supplement er en ny sugetablet udviklet med naturlige ingredienser.<\/span><\/p>\n

Metode
\n<\/span><\/strong>I et dobbeltblindet, randomiseret kontrolleret studie blev 350 b\u00f8rn i alderen 5\u20139 \u00e5r fra fire kommuner i Nordsj\u00e6lland inddelt i to grupper. Den ene gruppe fik dagligt en sugetablet med L-arginin og m\u00e6lkesyrebakterier i et \u00e5r, mens kontrolgruppen fik placebo. Alle b\u00f8rn fortsatte med daglig tand-b\u00f8rstning med fluoridtandpasta.<\/span><\/p>\n

Resultater
\n<\/span><\/strong>288 b\u00f8rn gennemf\u00f8rte studiet. Carieserfaringen blev m\u00e5lt som \u00e6ndring i antallet af tandflader med caries, fyldninger eller mistede t\u00e6nder pga. caries. I placebogruppen steg carieserfaringen med gennemsnitligt 0,49 tandflader pr. barn, mens stigningen i testgruppen kun var 0,09. Dette svarer til en reduktion p\u00e5 ca. 82 %. Effekten s\u00e5s b\u00e5de i m\u00e6lket\u00e6nder og i 6-\u00e5rstanden. Resultatet er sammen-ligneligt med den beskyttelse, man ser ved brug af fluoridtandpasta.<\/span><\/p>\n

Diskussion
\n<\/span><\/strong>L-arginin findes naturligt i spyt og nedbrydes af bakterier i munden til en base, som h\u00e6ver pH og dermed beskytter emaljen mod syreangreb. Dette \u00e6ndrer samtidig mundmilj\u00f8et, s\u00e5 det bliver mere gavnligt for de gode bakterier. M\u00e6lkesyrebakterierne i sugetabletten konkurrerer med de cariesfremkaldende bakterier om plads og n\u00e6ring, hvilket underst\u00f8tter en sundere balance i mundens mikrobiota.<\/span><\/p>\n

Konklusion
\n<\/span><\/strong>Daglig brug af en sugetablet med L-arginin og m\u00e6lkesyrebakterier reducerede b\u00f8rns carieserfaring markant, selv ved samtidig brug af fluoridtandpasta.<\/span><\/p>\n

Implikationer for praksis
\n<\/span><\/strong>Sugetabletten kan fungere som et supplement til eksisterende forebyggelsesstrategier. Den kan v\u00e6re relevant ikke kun for b\u00f8rn, men ogs\u00e5 voksne med forh\u00f8jet cariesrisiko, fx patienter med mundt\u00f8rhed for\u00e5rsaget af medicin (over 1.500 l\u00e6gemidler), diabetes, astma eller kr\u00e6ftbehandling.<\/span><\/p>\n

L\u00e6s mere om den danske sugetablet HER<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

P\u00f8rksen CJ, Keller MK, Damholt A, Frederiksen AKS, Ekstrand KR, Markvart M, Larsen T, Bakhshandeh A. The effect of a 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