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Af Line Trier Friis og Mathilde Hermansen, stiftere af Hormonehealthdk<\/a><\/p>\n Resume<\/strong>: Et systematisk review fra 2025 unders\u00f8ger smerter relateret til menopause-transitionen og identificerer hormonelle \u00e6ndringer, s\u00f8vnforstyrrelser, muskuloskeletale problemer og psykologiske symptomer som centrale faktorer. Studiet fremh\u00e6ver b\u00e5de medicinske og ikke-medicinske behandlingsstrategier, herunder hormonbehandling, kost\u00e6ndringer og motion. \u00d8strogenniveauets fald spiller en central rolle i \u00f8get smertef\u00f8lsomhed.<\/p>\n<\/div>\n Et systematisk review fra 2025 med titlen: “Pain during menopause” fra International Association for the Study of Pain (IASP) unders\u00f8ger forskellige former for smerter, som kvinder kan opleve i forbindelse med menopause-transitionen. <\/span> <\/span><\/p>\n Form\u00e5let<\/span><\/b> med artiklen er at give en omfattende gennemgang af de faktorer, der bidrager til smerte i menopause-transitionen, Herunder hormonernes indvirkning p\u00e5 smerte, og en gennemgang af behandlingsstrategier for smerter- b\u00e5de farmakologiske og ikke-farmakologiske tilgange.<\/span> <\/span><\/p>\n Vi har samlet de vigtigste resultater her:<\/span> <\/span><\/p>\n Faktorer, der bidrager til smerter<\/span><\/b>:<\/span> Vasomotoriske symptomer:<\/strong> Menopause-transitionen medf\u00f8rer mange fysiologiske og symptomatiske \u00e6ndringer, hvor vasomotoriske symptomer som hede- svedeture er blandt de mest genkendelige. Hede- svedeture kan forstyrre s\u00f8vnen, hvilket kan f\u00f8re til problemer som s\u00f8vnl\u00f8shed, irritabilitet, hukommelsestab og koncentrationsbesv\u00e6r. Disse s\u00f8vnforstyrrelser er associeret med \u00f8get smertef\u00f8lsomhed hos kvinder.<\/span> <\/span><\/p>\n Muskel-led- og skeletproblemer:<\/strong> Fald af \u00f8strogen kan f\u00f8re til flere smerter \u2013 herunder lavere knoglet\u00e6thed, som kan f\u00f8re til osteoporose og smerter, is\u00e6r i rygs\u00f8jlen, stive og \u00f8mme led samt nedbrydning af ledv\u00e6v, som af flere giver smerter i h\u00e6nder, kn\u00e6 og hofter. Et systematisk review fra 2020 med 16 inkluderede studier viste,<\/span> at kvinder i perimenopausen har en h\u00f8jere risiko for at udvikle muskuloskeletale smerter sammenlignet med pr\u00e6-menopausale kvinder. Risikoen for moderate til sv\u00e6re muskuloskeletale smerter \u00f8ges yderligere i postmenopausen.<\/span> <\/span><\/p>\n Psykologiske symptomer:<\/strong> Mange kvinder oplever psykologiske symptomer \u2013 fx som f\u00f8lge af fald i progesteron – s\u00e5som depression, irritabilitet, tr\u00e6thed og s\u00f8vnforstyrrelser. S\u00f8vnl\u00f8shed kan forv\u00e6rre kroniske smerter, og kvinder i menopause-transitionen har en h\u00f8jere risiko for s\u00f8vnapn\u00f8, som kan \u00f8ge smertef\u00f8lsomheden. S\u00f8vnapn\u00f8 og s\u00f8vnforstyrrelser kan f\u00f8re til fragmenteret s\u00f8vn og \u00f8get inflammation, som kan forst\u00e6rke smerteoplevelsen.<\/span> <\/span><\/p>\n Ikke-medicinske og medicinske tiltag <\/span><\/b>kan lindre smerter i menopause-transitionen. Studier viser, at kost\u00e6ndringer som plantbaserede di\u00e6ter og soja kan reducere ledsmerter og hovedpine. Bedre s\u00f8vnkvalitet kan mindske smerteintensiteten. Motion og fysioterapi, is\u00e6r pilates og sv\u00f8mning, kan lindre rygsmerter. <\/span> <\/span><\/p>\n Medicinske behandlinger<\/span><\/b>: Hormonbehandling er mange steder standardbehandlingen for muskuloskeletale smerter i menopause-transitionen. Studier viser, at \u00f8strogenbehandling kan reducere ledsmerter, men kan ogs\u00e5 \u00f8ge h\u00e6velse i led. Hormoncremer kan hj\u00e6lpe med smerter i hofteomr\u00e5det, is\u00e6r n\u00e5r de kombineres med motion. Lokale hormonbehandlinger med \u00f8strogen kan ogs\u00e5 forbedre seksuel funktion og reducere smerter ved samleje. <\/span> <\/span><\/p>\n Studiet konkluderer<\/span><\/b>, at der fortsat mangler viden for at kunne forst\u00e5 smerter i menopause-transitionen og hvordan man kan lindre disse for at \u00f8ge livskvaliteten hos de ber\u00f8rte kvinder. <\/span> <\/span><\/p>\n *<\/strong>Vil du vide mere om de forskelle begreber omkring overgangsalder og menopause, s\u00e5 l\u00e6s vores opslag her: Vi h\u00e5ber du har f\u00e5et mere viden om <\/span>smerter i menopause-transitionen<\/span> og er blevet nysgerrig p\u00e5 at l\u00e6re endnu mere. For mere indhold som dette, f\u00f8lg med p\u00e5 @hormonehealthdk. <\/strong><\/span> Kilder Smerter i menopause-transitionen* Af Line Trier Friis og Mathilde Hermansen, stiftere af Hormonehealthdk Resume: Et systematisk review fra 2025 unders\u00f8ger 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\n<\/span>Hormonelle forandringer:<\/strong> N\u00e5r kvinder er i menopause-transitionen, falder niveauerne af \u00f8strogen, som kan \u00f8ge smertef\u00f8lsomheden. \u00d8strogen p\u00e5virker smerteopfattelsen ved at virke p\u00e5 opioidreceptorer og regulere frigivelsen af endorfiner. Med faldet i \u00f8strogen kan kvinder i overgangsalderen derfor opleve mere smerte p\u00e5 grund af disse hormonelle \u00e6ndringer.<\/span> <\/span><\/p>\n\n
\nMenopause-transitionen – begreber og terminologier<\/a><\/p>\n
\nsygeplejevidenskab<\/a> instagram<\/a> <\/span><\/span>Facebook<\/a><\/span> LinkedIn<\/a> <\/span><\/span> <\/span><\/p>\n<\/div>\n
\n<\/strong>Strand, N.H. et al., 2025. Pain during menopause: link<\/a>
\n<\/span>Schertzinger, M. et al., 2018. Daily Fluctuations of Progesterone and Testosterone Are Associated With Fibromyalgia Pain Severity: link<\/a><\/span> <\/span>
\n<\/span>Lu, C. et al., 2020. Musculoskeletal Pain during the Menopausal Transition: A Systematic Review and Meta-Analysis: link<\/a><\/span> <\/span> <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"