{"id":10997,"date":"2024-12-16T16:19:48","date_gmt":"2024-12-16T15:19:48","guid":{"rendered":"https:\/\/sygeplejevidenskab.dk\/?p=10997"},"modified":"2024-12-16T16:19:48","modified_gmt":"2024-12-16T15:19:48","slug":"nsaid-sammen-med-antikoagulantia-fordobler-risiko-for-indre-bloedninger","status":"publish","type":"post","link":"https:\/\/sygeplejevidenskab.dk\/index.php\/2024\/12\/16\/nsaid-sammen-med-antikoagulantia-fordobler-risiko-for-indre-bloedninger\/","title":{"rendered":"NSAID sammen med antikoagulantia fordobler risiko for indre bl\u00f8dninger"},"content":{"rendered":"

\"\"<\/p>\n

Patienter i blodfortyndende behandling, der tager NSAID-pr\u00e6parater som smertestillende, fordobler deres risiko for indre bl\u00f8dninger i s\u00e6rligt mave-tarm-kanalen, hjerne, lunger og bl\u00e6re.<\/p>\n

Det viser et stort studie<\/a> fra Aarhus Universitetshospital publiceret i European Heart Journal som er referereret i Medicinske Tidsskrifter<\/a><\/p>\n

Forskerne benyttede data fra danske landsd\u00e6kkende registre. I studiet indgik 51.794 personer, der modtog antikoagulantia til behandling af blodprop i benene eller lungerne i perioden 2012 til 2022. De s\u00e5 p\u00e5 NSAID-pr\u00e6paraterne Diclofenac, Naproxen som er receptpligtig og Ibuprofen som er h\u00e5ndk\u00f8b. <\/p>\n

Risikoen for en bl\u00f8dning i mave-tarm-kanalen ved brug af et NSAID -pr\u00e6parat var 2,24 gange h\u00f8jere. Risikoen for en bl\u00f8dning i hjernen var 3,22 gange h\u00f8jere. I lungerne var risikoen for en bl\u00f8dning \u00f8get med 1,36 gange. I urinvejene var risikoen for en bl\u00f8dning 1,57 gange h\u00f8jere. Der var ligeledes n\u00e6sten en tredobling af risikoen for an\u00e6mi for\u00e5rsaget af bl\u00f8dning.<\/p>\n

Forskerne kiggede p\u00e5 flere typer blodfortyndende midler \u2013 herunder Rivaroxaban, Apixaban, Dabigatran, Edoxaban og Warfarin \u2013 og fandt et lignende risikom\u00f8nster.<\/p>\n

Samlet set fandt forskerne, at risikoen for en bl\u00f8dning var 2,09 gange h\u00f8jere, hos personer, som tog et NSAID-pr\u00e6parat og et blodfortyndende middel, sammenlignet med dem, der tog et blodfortyndende middel og intet NSAID-pr\u00e6parat. Risikoen ved brug af Ibuprofen var 1,79 gange h\u00f8jere, for Diclofenac var risikoen 3,3 gange h\u00f8jere og for Naproxen var risikoen 4,1 gange h\u00f8jere. L\u00e6s den videnskabelige artikel her: <\/p>\n

European Heart Journal<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Patienter i blodfortyndende behandling, der tager NSAID-pr\u00e6parater som smertestillende, fordobler deres risiko for indre bl\u00f8dninger i s\u00e6rligt mave-tarm-kanalen, hjerne, lunger […]<\/p>\n","protected":false},"author":1,"featured_media":10998,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_ppp_document_settings_meta":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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